Lake house holiday rentals in South Carolina
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in South Carolina
Guests agree: these lake houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina lake house rentals
Waterfront lakehouse rentals
Home in Chappells
4.95 out of 5 average rating, 145 reviewsGreenwood Lake Front, FirePit, Outside Kitch, Dock
28 Jan – 4 Feb
Home in Inman
4.95 out of 5 average rating, 103 reviewsMaggie's Lake House
12–19 Oct
Home in Inman
4.93 out of 5 average rating, 230 reviewsLakingitEz..3BR/2BA amazing sunsets & hot tub
15–22 Dec
Home in Ridgeway
4.96 out of 5 average rating, 111 reviews3000 sq ft lake house with views from every window
27 Oct – 3 Nov
Home in Inman
4.99 out of 5 average rating, 149 reviewsLAKE LIFE...
30 Mar – 6 Apr
Home in Chapin
4.9 out of 5 average rating, 104 reviewsLake Murray Family Retreat | BIG Water View Chapin
16–23 Dec
Home in Myrtle Beach
4.91 out of 5 average rating, 190 reviewsPrivate Beach Paradise in Ocean Lakes w/ Golf Cart
29 Dec – 5 Jan
Home in Fair Play
4.96 out of 5 average rating, 48 reviewsWaterfall Cove - East
19–26 Jul
Pet-friendly lake house rentals
Home in Bluffton
4.98 out of 5 average rating, 123 reviewsOld Town Bluffton Cottage - Includes Golf Cart!
4–11 Feb
Home in Inman
4.95 out of 5 average rating, 102 reviewsCasa del Lago...Come Relax...You are on Lake Time!
27 Feb – 6 Mar
Home in Modoc
4.93 out of 5 average rating, 104 reviewsIvy’s Escape (water front) at Lake Thurmond
29 Jul – 5 Aug
Home in Easley
4.92 out of 5 average rating, 133 reviewsLarge lake house - 15 min to Downtown Greenville
8–15 Apr
Home in Anderson
4.99 out of 5 average rating, 138 reviewsLake House, close to Clemson Kayaks & Paddleboards
7–14 Jul
Home in Hilton Head Island
4.92 out of 5 average rating, 106 reviewsLuxe & Fun Family Gem ~ Walk to Beach ~ Pool ~ BBQ
11–18 Feb
Home in Lexington
4.87 out of 5 average rating, 143 reviewsLake Murray Paradise~2 BR, 1 Bth, Kit/Living area.
13–20 Oct
Home in Seneca
4.85 out of 5 average rating, 174 reviewsCozy Lake House 5 miles from Clemson w Dock
13–20 Dec
Private lake house rentals
Home in Ridgeville
4.82 out of 5 average rating, 191 reviewsFarm House Lodge at Natural Gathering Grounds
7–14 Aug
Home in Gilbert
4.96 out of 5 average rating, 134 reviews10 Mile View on Lake Murray w/ Dock and Ramp
13–20 Oct
Home in Tamassee
5.0 out of 5 average rating, 24 reviewsWhitewater Lake Front Cottage
30 Dec – 6 Jan
Home in Cross Hill
5.0 out of 5 average rating, 4 reviewsLakeside Paradise!
23–30 Aug
Home in Summerton
5.0 out of 5 average rating, 81 reviewsCheerful 3 bedroom home on the lake
31 Dec – 7 Jan
Home in Ninety Six
5.0 out of 5 average rating, 25 reviewsLakefront Retreat
12–19 Dec
Home in Branchville
4.93 out of 5 average rating, 30 reviewsEdisto River Turnhole Getaway
5–10 Aug
Home in Anderson
4.99 out of 5 average rating, 68 reviewsLakefront dock *Hot tub* Anderson Clemson King bed
11–18 Jul
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