Guest house holiday rentals in South Carolina

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in South Carolina

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

0 of 0 items showing

1 of 3 pages

Guest favourite

Guest house in Abbeville

4.97 out of 5 average rating, 287 reviews

Quiet, Peaceful Loft in the Woods

Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

6–13 Jun

€ 66 per night

Guest favourite

Guest house in Beaufort

4.96 out of 5 average rating, 210 reviews

Sunset River House

Our quaint little River House rests on the beautifully natural marsh grass banks of the Whale Branch River in a quiet rural neighborhood. It is located only 9 miles from Historic Downtown Beaufort and 15 miles from Parris Island Marine Corps Recruit Depot. Hunting Island State Park's sandy beaches, nature tails, and lighthouse tours are a scenic 40 minute drive away. You can swim, fish, kayak or go boating right from the dock in our own back yard. When you arrive; you won't want to leave!

25 Sep – 2 Oct

€ 116 per night

Guest favourite

Guest house in Fort Mill

4.96 out of 5 average rating, 134 reviews

Carriage House Suite on Lake Wylie

The view! Our peaceful studio has everything you need to enjoy your time with us including an amazing view of the lake. It has a full kitchen, tiny bathroom and laundry. It’s close to a LOT of outdoor activities: swimming, boating, river rafting/kayaking, golfing, zip lining, biking, hiking, and walking. From studio, its only 15 minutes to Carowinds Amusement park, 25 minutes to Charlotte, NC or Airport. An easy drive to big city attractions. At days end, relax and enjoy dinner by the lake!

24–31 Oct

€ 164 per night

Guest favourite

Guest house in Greenwood

4.94 out of 5 average rating, 181 reviews

Private Lakefront Cabin on Lake Greenwood

Get ready to enjoy beautiful lake views from this home! Private lake house right on Lake Greenwood. This recently remodeled guest house has one bedroom with a queen bed, full bath, and a large main room with a huge sectional sofa. Strong WIFI. 50" tv: Roku/Netflix/Hulu equipped. Enjoy 128ft of lakeshore including a fire pit, concrete pier, pergola seating area, beach, swimming area in lake, and putting green. 2 Kayaks available, free to use. 20ft pontoon for rent based on availability.

23–28 Jun

€ 174 per night

Guest favourite

Guest house in Sunset

4.92 out of 5 average rating, 344 reviews

Mountain Cabin on Creek at Jocassee Gorge.

Welcome to Laurel Valley. A tiny, sleepy neighborhood at the top of a mountain, hidden from the hustle of civilization. This adorable cabin is nestled in beautiful Jocassee Gorge. Minutes away from multiple attractions including Sassafras Mountain and Twin Falls. Property borders thousands of acres of protected land with 5 star trails . This mountain cabin is in a unique setting that time forgot. The rushing creek outside helps you to peel off the world and get a great night's sleep.

31 Aug – 7 Sep

€ 152 per night

Guest favourite

Guest house in Greenville

4.99 out of 5 average rating, 358 reviews

The Cottage at Old Oaks Farm

Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

26 Mar – 2 Apr

€ 117 per night

Guest favourite

Guest house in Beaufort

4.98 out of 5 average rating, 439 reviews

Peace Point

Come and enjoy Peace Point's beautiful views of the Broad River and huge oak trees with the Spanish moss. It is just a walk away from the Broad River fishing pier which showcases beautiful sunsets! It is also just minutes away from Parris Island & MCAS. Peace Point is a private guest house with a king size bed and queen sofa sleeper with an amazingly comfortable Tempurpedic mattress.The guesthouse has a beachy vibe with calming colors. It has a small freezer/fridge and microwave.

28 Sep – 5 Oct

€ 114 per night

Guest favourite

Guest house in Beaufort

4.98 out of 5 average rating, 203 reviews

Buddy's Cottage near everything in Beaufort, SC

Who is Buddy? He was our black Labrador of 12 years. You'll see his photo as you enter. This brand new guest cottage has a private bedroom, 1 full bathroom, a sleeper sofa , 2 TV's, a full kitchen and all the amenities of home. Downtown Beaufort is 2 miles away, Parris Island is less than 5 miles away. In a quiet neighborhood. Are coming for a fishing trip and bringing your boat? Come stay with us , we have room for your boat. You can flush your engine and rinse your boat down.

27 Sep – 4 Oct

€ 141 per night

Guest favourite

Guest house in Florence

4.93 out of 5 average rating, 686 reviews

The Poolside Cottage: Close to Interstates

New floors and paint in January of 2023. Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, queen sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

16–23 Oct

€ 104 per night

Guest favourite

Guest house in Camden

4.91 out of 5 average rating, 271 reviews

Camden Coach House Long term stay southern balance

Renovated 10/2023 Experience Camden like ancestors in last large tract of land bordering business district and horse community. Hike 4mi private trails connect Springdale stable, Camden country club between work on 500mb inet. No lost power generator keeps you connected. Southern custom Tulip maple sink, Spa Shower, 200 year old barn door, board n batten exterior surrounds you in history. ・24/7 pro staff ・Security gate, cams ・Full kitchen ・Laundry ・Fountains ・gardens ・pond

1–8 Oct

€ 118 per night

Guest favourite

Guest house in Rock Hill

4.98 out of 5 average rating, 112 reviews

Cove Cottage, Lakefront Retreat + Kayaks

Find true rest or spark creative genius at this unique and tranquil getaway. Created for the solo retreat or a couples weekend away, this studio space offers the perfect backdrop in nature. You will find yourself surrounded by beauty whether that be curled up inside with large windows facing acres of woodland wearing the colors of the season, or near the calm water on our cove.

8–15 Jan

€ 119 per night

Guest favourite

Guest house in West Columbia

4.94 out of 5 average rating, 600 reviews

Carriage House: Studio Bed & Bath - Pool & Hot Tub

Minutes from Lexington Medical Center, USC, Lake Murray, River Bank Zoo, Downtown Columbia and CAE Airport! Secluded stand alone Garage Carriage House w/Upstairs private studio bedroom with a full size bath on main floor. Enjoy your private patio, garden, grill, and so much more! Guest are welcome to enjoy our Beautiful Salt-water Pool with Gorgeous Night Lighting.

8–15 Aug

€ 110 per night