Guest house holiday rentals in San Diego
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in San Diego
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in San Diego
Family-friendly guest house rentals
Guest house in San Diego
4.97 out of 5 average rating, 508 reviewsCentral & Serene Secret Garden Guesthouse
15–22 Sep
Guest house in Chula Vista
4.95 out of 5 average rating, 476 reviewsPrivate Casita in Great Eastlake Neighborhood
24–31 Oct
Guest house in El Cajon
4.98 out of 5 average rating, 191 reviewsFletcher Hills - modern 1 BR.Easy, no step access.
24 Sep – 1 Oct
Guest house in Oceanside
4.92 out of 5 average rating, 266 reviewsThe Sunshine House. Location, Location, Ocean.
29 Oct – 5 Nov
Guest house in San Diego
4.97 out of 5 average rating, 292 reviewsPrivate Guest House with a View
8–15 Aug
Guest house in San Diego
4.95 out of 5 average rating, 474 reviewsRomantic Private Garden Studio Near Downtown
7–14 Dec
Guest house in San Diego
4.99 out of 5 average rating, 364 reviews*Private Canyon Retreat: Your Own Guesthouse*
9–16 Jan
Guest house in San Diego
4.94 out of 5 average rating, 333 reviewsThe BEST NEST Clean, peaceful, private, affordable
8–15 Feb
Guest house rentals with a patio
Guest house in San Diego
5.0 out of 5 average rating, 108 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
24–31 Oct
Guest house in La Mesa
4.98 out of 5 average rating, 251 reviewsLa Mesa Suite
6–13 Oct
Guest house in San Diego
4.98 out of 5 average rating, 124 reviewsPrivate Studio Cottage with Outdoor Patio
19–26 Dec
Guest house in San Diego
4.91 out of 5 average rating, 151 reviewsCentral studio w/ private outdoor space & parking
11–18 Dec
Guest house in San Diego
4.96 out of 5 average rating, 104 reviewsCozy Urban Casita! Near Zoo, Gaslamp and Coronado
13–20 May
Guest house in Poway
4.99 out of 5 average rating, 117 reviews⭐️Garden studio guesthouse, resort living with pool
Guest house in San Diego
4.99 out of 5 average rating, 151 reviewsAdorable cottage in Talmadge
18–25 Jan
Guest house in San Diego
4.99 out of 5 average rating, 142 reviewsMission Hills-Entire Guest House-Center of it All
5–10 May
Guest house rentals with a washing machine and dryer
Guest house in San Diego
4.87 out of 5 average rating, 418 reviewsThe Golden Hill mosaic "casita"
7–12 Jul
Guest house in San Diego
4.95 out of 5 average rating, 294 reviews*BEAUTIFUL* Sunny Home in Golden Hill
Guest house in San Diego
4.91 out of 5 average rating, 152 reviewsRelaxing Oasis - short walk to shops & recreation
16–23 Sep
Guest house in San Diego
4.96 out of 5 average rating, 117 reviews1BR Casita in the Heart of Kensington!
16–23 Sep
Guest house in San Diego
4.97 out of 5 average rating, 306 reviewsPrivate Guesthouse in Trendy North Park
8–15 Jun
Guest house in San Diego
4.9 out of 5 average rating, 193 reviewsSTUNNING Casita with a View!!
15–22 Oct
Guest house in Valley Center
4.91 out of 5 average rating, 211 reviewsNorth San Diego Serenity
15–22 Apr
Guest house in La Mesa
4.99 out of 5 average rating, 133 reviewsStunning Guest House 15 min. from Zoo, Downtown
27 Aug – 3 Sep
Quick stats about guest house rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
Destinations to explore
- Tijuana Holiday rentals
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