Guest house holiday rentals in Charleston County
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Charleston County
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Charleston County
Family-friendly guest house rentals
Guest house in North Charleston
4.94 out of 5 average rating, 346 reviewsCozy Park Circle, Charleston Guest House
1–8 Sep
Guest house in Summerville
4.98 out of 5 average rating, 645 reviews★Delightful guest house near historic plantations★
21–28 Dec
Guest house in Summerville
4.94 out of 5 average rating, 212 reviewsNina's Cottage -Historic Downtown Summerville
25 Sep – 2 Oct
Guest house in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
3–10 Sep
Guest house in Charleston
4.91 out of 5 average rating, 650 reviewsIsland Oasis—Near Downtown
21–28 Oct
Guest house in Summerville
4.87 out of 5 average rating, 749 reviewsNew Loft in Historic Summerville
4–11 Jan
Guest house in North Charleston
4.86 out of 5 average rating, 442 reviewsPark Circle Jungalow Loft
16–23 Sep
Guest house in Johns Island
4.98 out of 5 average rating, 240 reviewsPrivate waterfront apt in the oaks
22 Feb – 1 Mar
Guest house rentals with a patio
Guest house in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
6–13 Jan
Guest house in Charleston
4.98 out of 5 average rating, 123 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
18–25 Feb
Guest house in Johns Island
4.91 out of 5 average rating, 108 reviewsCozy Cottage! 5 mins from Kiawah!
18–25 Sep
Guest house in Goose Creek
4.96 out of 5 average rating, 50 reviewsThe Blue Secret
17–24 Jul
Guest house in Charleston
4.98 out of 5 average rating, 46 reviewsCountry in the City, "The Outback"
11–18 Dec
Guest house in Hanahan
4.99 out of 5 average rating, 78 reviewsThe Violet Villa w/ no cleaning fee
26 Aug – 2 Sep
Guest house in Charleston
5.0 out of 5 average rating, 13 reviewsLowcountry Guesthouse
28 Jul – 4 Aug
Guest house in Charleston
4.94 out of 5 average rating, 79 reviewsSpacious 1 bedroom cottage in Avondale
14–21 Dec
Guest house rentals with a washing machine and dryer
Guest house in Charleston
4.98 out of 5 average rating, 245 reviewsDetached Guest Suite
11–18 Apr
Guest house in Charleston
4.9 out of 5 average rating, 549 reviewsCute, Cozy, Charleston Cottage
22–29 Aug
Guest house in Charleston
4.99 out of 5 average rating, 144 reviewsLarge Guesthouse with Private Dock & Marsh Views
13–20 Dec
Guest house in Charleston
5.0 out of 5 average rating, 217 reviewsJames Island "La Casita" Nestled btw Beach & City
9–16 Oct
Guest house in Mount Pleasant
4.98 out of 5 average rating, 437 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
2–9 Sep
Guest house in Charleston
4.98 out of 5 average rating, 108 reviewsCharleston Casita near Folly Beach *Dog Friendly*
31 Jan – 7 Feb
Guest house in Charleston
5.0 out of 5 average rating, 144 reviewsThe Guesthouse at Old Orchard
28 Aug – 4 Sep
Guest house in Mount Pleasant
4.98 out of 5 average rating, 116 reviewsBeach, downtown, Alhambra Hall weddings so close!
19–26 Oct
Destinations to explore
- House rentals United States
- Guest house rentals United States
- House rentals Myrtle Beach
- Guest house rentals Charleston
- House rentals Charleston
- House rentals Savannah
- Guest house rentals Savannah
- Guest house rentals South Carolina
- House rentals South Carolina
- Rentals with a washing machine and dryer Charleston County
- Hotel rentals Charleston County
- Rentals with outdoor seating Charleston County
- Beachfront rentals Charleston County
- Rentals with beach access Charleston County
- Waterfront rentals Charleston County
- Family-friendly rentals Charleston County
- Rentals with a patio Charleston County
- House rentals Charleston County
- Pet-friendly rentals Charleston County
- Rentals with a kayak Charleston County
- Rentals with lake access Charleston County
- Flat rentals Charleston County
- Rentals with a hot tub Charleston County
- Family-friendly rentals Charleston County
- Rentals with a firepit Charleston County
- Luxury rentals Charleston County
- Rentals with a fireplace Charleston County
- Monthly Rentals Charleston County
- Villa rentals Charleston County
- Rentals with breakfast Charleston County
- Bed and breakfasts Charleston County
- Rentals with an accessible-height toilet Charleston County
- Fitness-friendly rentals Charleston County
- Apartment rentals Charleston County
- Rentals with an EV charger Charleston County
- Tiny house rentals Charleston County
- Rentals with pools Charleston County
- Bungalow rentals Charleston County
- Townhouse rentals Charleston County
- Private suite rentals Charleston County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom