Mansion holiday rentals in Panama
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Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama mansion rentals
Luxury mansion rentals
Villa in Panamá
5.0 out of 5 average rating, 31 reviewsBreathtaking Views Mansion w/King Beds
Home in Río Hato
4.95 out of 5 average rating, 75 reviewsSpectacular beachfront house in Buenaventura!
Villa in Playa Venao
4.98 out of 5 average rating, 61 reviewsCasa Aqua: Amazing beach front house - Playa Venao
Flat in Panama City
4.68 out of 5 average rating, 250 reviewsPenthouse with rooftop and pool 5 rooms Di5
Villa in Punta Chame
4.92 out of 5 average rating, 13 reviewsFREE NIGHT Amazing Beachfront Villa - Palm House
Flat in Maria Chiquita
4.95 out of 5 average rating, 20 reviewsPenthouse in Playa Escondida 4 bedrooms
Townhouse in Buenaventura, El Chirú
4.86 out of 5 average rating, 44 reviewsLake House | Private Pool | King Bed | Sleeps 14
Villa in Bejuco
4.96 out of 5 average rating, 78 reviewsBeach house in Punta Chame, Villa frente al mar
Pet-friendly mansion rentals
Cottage in Altos del Maria
4.93 out of 5 average rating, 99 reviewsCabin with Spectacular Mountain View
Home in Playa Bluff
5.0 out of 5 average rating, 16 reviewsJungle House 100m from the beach
Flat in San Carlos District
4.99 out of 5 average rating, 79 reviewsAmazing Oceanfront apartment in San Carlos
Villa in Portobelo
5.0 out of 5 average rating, 42 reviewsEntire Villa with pool in front of beach!
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
Villa in Costa Esmeralda
5.0 out of 5 average rating, 13 reviewsSpectacular 600-meter oceanfront beach house
Apartment in San Carlos District
4.97 out of 5 average rating, 37 reviewsPunta Caelo Beach Front View
Villa in Bocas del Toro
5.0 out of 5 average rating, 56 reviewsCasa del Mar - eco aqua villa
Mansion rentals with a pool
Apartment in Maria Chiquita
5.0 out of 5 average rating, 19 reviewsPlaya Escondida Lux Beachfront Haven:Oceanview Apt
Flat in Panamá
5.0 out of 5 average rating, 21 reviewsTop Floor Condo 6 bedroom with amazing views
Flat in Maria Chiquita
4.97 out of 5 average rating, 59 reviewsSpacious 4Br Beachside Getaway at Playa Escondida
Flat in Río Hato
5.0 out of 5 average rating, 18 reviews4 Bedroom Private Pool Paradise in Buenaventura
Home in Cacique
5.0 out of 5 average rating, 19 reviewsEl Paraiso
Flat in Panama City
5.0 out of 5 average rating, 20 reviews24o Penthouse Unique Design 2 Balconies Oceanview
Flat in El Chirú
4.94 out of 5 average rating, 84 reviewsBuenaventura Golf & Beach Resort Lux Apartment
Home in Palenque
5.0 out of 5 average rating, 4 reviewsCaribbean Paradise - Beachfront Getaway
Destinations to explore
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