Holiday rentals in Isthmus of Panama

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Top-rated holiday rentals in Isthmus of Panama

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite

Cabin in Torio

4.97 out of 5 average rating, 105 reviews

Cozy open space, unique jungle views, river access

Casa Corotu is located in Torio Hills a 10 minute's walk to the beach with a a trail to access Torio river. Fiber Optic WiFi and two work spaces. The property surrounded by big trees that keep the house cool, which also provide shelter for birds and wildlife. The house is NOT childproof, minimal railing system. It's a great house to live the experience of #toriolife and all it has to offer. It is also an opportunity to experience the jungle in an open-style home with a mesmerizing treetop view.

Guest favourite

Home in Costa Esmeralda

4.96 out of 5 average rating, 107 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sand! Come relax with the whole family at this piece of paradise. Majestic Sand is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.

Guest favourite

Flat in Panamá

4.95 out of 5 average rating, 42 reviews

Aparta estudio de lujo completo en Panamá.

Ubicado en San Francisco, una de las zonas exclusivas por excelencia en Panamá, donde la gastronomía, historia, modernidad y entretenimiento se combinan mágicamente. Maravillosa ubicación cerca de destinos imperdibles, gimnasio, piscina, coworking, pet spa y terraza. El estacionamiento tiene cobro. Moderno y funcional, este apartamento cuenta con una habitación cama queen, cocina completamente equipada, Wifi, televisión, un balcón espectacular con vista al mar, centro de lavado y sofá cama.

Superhost

Earthen home in El Cope, Penonome

4.91 out of 5 average rating, 148 reviews

Beautiful Eco House in Panama

We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.

Guest favourite

Townhouse in Panamá

4.97 out of 5 average rating, 162 reviews

Casa Casco Amigos - The Only House in Casco.

Located by the French Embassy in Casco Viejo in the absolute safest and most prestigious area of Panama City, Casa Casco Amigos is a 3 level, 3 bedroom 351 square meter house with a roof terrace and a garden terrace which can sleep 9. Despite the liveliness of the area, there is no noise whatsoever in the bedrooms. Perfect for 1 or 2 families, or a group of 6 to 9 friends who want to be in the heart of the old city, with a sea view and many areas to lounge and avoid the midday heat.

Guest favourite

Guest house in La Ermita de San Carlos

4.97 out of 5 average rating, 110 reviews

Sky Cabin/playas/piscina/surf/nómadas digitales

The Sky Cabin is part of 5 cabins “A Piece of Paradise” With registration in the Panamanian Tourism Authority Bureau. ✸ Ideal for a couple or a single person ✸ Outdoor dining area and kitchen ✸ Spacious terrace with a hammock ✸ Very quiet neighborhood ✸ Private and public transportation available, just ask and we will help you ✸ 7-10 minutes, by car, from Playa La Ermita and 10 minutes from Playa El Palmar (great spot for surfing) ✸ Breakfast for an additional $7.00, for each guest.

Guest favourite

Home in Taboga Island

4.97 out of 5 average rating, 144 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Superhost

Treehouse in Provincia de Bocas del Toro

4.92 out of 5 average rating, 202 reviews

Cocovivo Mangrove Treehouse

This secluded loft-style treehouse sits on stilts above the water, 30 feet from our colorful coral reef. Transparent and airy but bug proof walls let you enjoy the fresh ocean breeze and views while keeping you safe and cozy. When a sloth comes to visit, no need to leave the house to see him! Blend in with the surroundings of mangrove, lagoon and jungle, and enjoy water and reef access from your own deck. Bright and airy, 100% eco-conscious.

Guest favourite

Cottage in Altos del Maria

4.93 out of 5 average rating, 100 reviews

Mountain Cottage with Great View and Heated Pool

Casa de Montaña, con espectacular vista a las montañas de Altos del María, perfecta para descansar o pasarla en familia, con piscina climatizada, amplios espacios exteriores, Smart TV y A/A en todas las habitaciones, WIFI en toda la propiedad y completamente equipada. Incluye servicio de Prime Video. Cuenta con área para hacer fogatas y un BBQ a gas. Para alquileres de fin de semana saliendo domingo, se da late check-out de cortesía.

Superhost

Home in Playa Venao

4.9 out of 5 average rating, 115 reviews

Beautiful Home Directly on Playa Venao Sleeps 8-10

This is our personal home and we take good care to make sure you thoroughly enjoy your stay! This home is located on the best surfing beach in the entire country. Walk out of your back door onto the sandy beach filled with wildlife and the best beach break for beginners to pros. This home offers luxury accommodations. This home is for families and respectful renters only. We do not accept groups who want to use the home to party.

Superhost

Treehouse in Isla Colon

4.95 out of 5 average rating, 133 reviews

Secret Jungle Treehouse by the Sea

A 2 bedroom treehouse built around a huge tree overlooking the lush jungle in a hidden setting. Artistically designed & comfortable; welcoming romantic souls, nature lovers & the adventurous. Enjoy nature in the harmony of an eco environment; ocean breezes, sound of waves, birds & monkeys. Spectacular sandy beaches only steps away. Surf, swim, bike, explore & live the adventure!. YouTube « Jungle Treehouse by the sea »

Superhost

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 226 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets.